Bon-Encontre, France

Curia – Bon-Encontre, France

API and intermediate development and manufacturing, from pilot batches to commercial tons.

Curia’s Bon-Encontre facility specializes in key areas of API and intermediate development and manufacturing, offering a range of technical services to advance drug programs. The site combines 143 m³ of total reactor volume and 150 metric tons of capacity with a commercial-scale continuous flow photochemistry reactor, under FDA and ANSM inspection.

Facility at a glance

Expertise

160+ experts

An experienced team spanning process optimization, commercial operations and technical services.

Total capacity

143 m³ reactor volume

143 m³ of total reactor volume support development through commercial campaigns.

Annual output

150 metric tons

Manufacturing capacity of 150 metric tons across the site’s production assets.

Batch scale

Up to 1,000 kg

Batch capability up to 1,000 kg bridges pilot campaigns into commercial supply.

Compliance

FDA and ANSM inspected

US and French regulatory inspection history supports worldwide commercial supply.

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Bon-Encontre site capabilities overview

What this site does

Photochemistry in continuous flow, at a ton per month

An innovative CSCPR-based commercial photo reactor delivers approximately one ton per month via optimized continuous processing, bringing photochemistry to commercial manufacturing scale.

From lab and pilot to commercial tons

Process optimization and commercial operations experience support quick scale-up from lab and pilot into commercial ton-scale manufacturing, with a set-up for controlled substances handling in place.

Cryogenic, organometallic and hazardous reagent handling

The site’s core activities include cryogenic reaction and organometallic synthesis, handling of hazardous reagents, and bromine handling under cGMP.

Why clients love this site

Photochemistry at commercial scale

CSCPR-based continuous photo reactor delivering at scale.

Built for commercial volumes

150 metric tons of capacity and 143 m³ of reactor volume take programs well beyond pilot scale.

Hazardous chemistry, handled

Bromine handling under cGMP, hazardous reagents, and cryogenic organometallic synthesis run as routine core activities.

Inspected on both sides of the Atlantic

FDA and ANSM inspection history supports supply into US and European markets.

How this site fits into Curia’s network

Tonneins, France – Monobactams and fine chemicals

Curia’s second French site runs dedicated sterile and non-sterile monobactam lines with more than 800 metric tons of fine chemicals capacity.

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Frankfurt, Germany – Fine chemicals and starting materials

Frankfurt adds phosphonic acid chemistry, hydrogenation and high-performance distillation for regulatory starting materials and fine chemicals.

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Springfield, MO – Large-scale US synthesis

Springfield mirrors Bon-Encontre’s large-scale and controlled substance capability in the US, with Schedule I-V manufacture at gram to metric ton scales.

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