Curia – Tonneins, France

Dedicated lines for sterile and non-sterile monobactams, plus 800+ metric tons of fine chemicals capacity.

Curia’s Tonneins facility runs dedicated lines for sterile and non-sterile monobactams, with suitability for excipients and beta-lactamase inhibitors, more than 800 metric tons of fine chemicals capacity and reconversion flexibility. The site operates 113 m³ of reaction volume under FDA and ANSM inspection.

Facility at a glance

Expertise

50+ experts

A focused team experienced in monobactam, excipient and fine chemicals manufacturing.

Reaction volume

113 m³

113 m³ of total chemical reaction volume across 34 reactors.

Fine chemicals

800+ metric tons

More than 800 metric tons of fine chemicals capacity with reconversion flexibility.

Equipment

34 reactors, 2 cryogenic

Glass-lined and stainless-steel reactors including two cryogenic units, four centrifuges and three filter dryers.

Compliance

FDA and ANSM inspected

US and French regulatory inspection history supports worldwide supply.

What this site does

Dedicated sterile and non-sterile monobactam lines

Tonneins operates dedicated manufacturing lines for both sterile and non-sterile monobactams, pairing with Curia’s Rozzano Valleambrosia site to give the network end-to-end depth in this specialized antibiotic class.

Suitability for excipients and beta-lactamase inhibitors

The site’s lines are suitable for excipients and beta-lactamase inhibitors, extending its regulated manufacturing beyond monobactam APIs.

800+ metric tons with reconversion flexibility

More than 800 metric tons of fine chemicals capacity, with reconversion flexibility, lets Tonneins adapt its assets to changing program needs.

A flexible, well-equipped reaction plant

113 m³ of reaction volume across 34 glass-lined and stainless-steel reactors, two cryogenic stainless-steel reactors, four centrifuges and three filter dryers support scale-up from development to large scale.

Why clients love this site

Monobactam specialization

Sterile capability in France

Flexibility built in

Inspected quality

How this site fits into Curia’s network

Curia’s dedicated Italian monobactam facility brings decades of aztreonam manufacturing experience, complementing Tonneins’ sterile and non-sterile lines.

Curia’s second French site adds continuous flow photochemistry, commercial ton-scale synthesis and controlled substances handling.

Valladolid contributes aseptic filtration and crystallization lines and high-potency capability to Curia’s European sterile API offering.

Frankfurt’s specialty fine chemicals and starting materials complement Tonneins’ fine chemicals capacity within the European network.

Curia lab worker talking with another team member

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