Valleambrosia, Italy

Curia – Rozzano Valleambrosia, Italy

A dedicated facility for monobactam APIs, with decades of aztreonam manufacturing experience.

Curia’s Rozzano Valleambrosia facility specializes in manufacturing monobactam active pharmaceutical substances by chemical synthesis. A dedicated monobactam facility with advanced process controls, 18.5 m³ of reaction volume and a reaction temperature range from roughly -50 to 200 °C, the site has been inspected by both the FDA and AIFA.

Facility at a glance

Expertise

25+ experts

A focused team with deep experience in monobactam chemistry and manufacturing.

Reaction volume

18.5 m³

18.5 m³ of reaction volume dedicated to monobactam synthesis.

Temperature range

-50 °C to 200 °C

Reaction temperatures from roughly -50 to 200 °C, including cryogenic capability in two reactors.

Reactor fleet

30 to 3,000 L

Reactors from 30 to 3,000 L in glass, stainless steel and glass-lined construction.

Compliance

FDA and AIFA inspected

US and Italian regulatory inspection history supports commercial supply.

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Rozzano Valleambrosia site capabilities overview

What this site does

A facility dedicated to monobactams

Rozzano Valleambrosia operates a dedicated facility for monobactam APIs with advanced process controls and decades of experience manufacturing aztreonam.

Cryogenic to high-temperature chemistry

The site runs chemistry across a reaction temperature range of roughly -50 to 200 °C, with cryogenic reactions supported in two reactors and a fleet of glass, stainless-steel and glass-lined reactors from 30 to 3,000 L.

FDA and AIFA inspected manufacture

FDA and AIFA inspection history supports regulated commercial supply, backed by the worldwide regulatory filing support of Curia’s generic API network.

Why clients love this site

Singular focus on monobactams

A dedicated facility means monobactam programs run without competing for capacity or risking cross-contamination from unrelated chemistries.

Decades of aztreonam experience

Long-running aztreonam manufacture gives the team rare, proven expertise in this specialized antibiotic class.

Advanced process controls

Modern process controls govern demanding chemistry across a -50 to 200 °C operating range.

Inspected quality

FDA and AIFA inspection history underpins supply into regulated markets.

How this site fits into Curia’s network

Tonneins, France – Sterile and non-sterile monobactams

Tonneins runs dedicated lines for sterile and non-sterile monobactams, making the two sites a paired capability for this antibiotic class within Curia’s network.

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