Fermentation Development & Manufacturing Services

From strain improvement and process development to scale-up and commercial manufacturing

End-to-end microbial fermentation and bioprocessing expertise, from strain improvement and process

Curia’s dedicated fermentation teams combines state-of-the-art facilities with expert knowledge to deliver customized solutions, from development to manufacturing. Our track record showcases unparalleled quality and regulatory compliance. With a multidisciplinary approach and versatile feedback control systems, we are adept at tackling challenges from benchtop experiments to full-scale production.

Image describes the scale of Curia's fermentation capabilities, from strain improvement and cell banking at discovery stage to large scale manufacturing at commercial stage
  • Microbial Strain Improvement: Conducted in cutting-edge labs with precision fermentation techniques, Curia is able to work with bacteria, yeast and fungi (both engineered and natural strains
  • Process Optimization: Scale-up capabilities for preclinical, clinical trials or manufacturing
  • Proven Success: A variety of case studies highlight Curia’s ability to rapidly deliver robust, cost-advantaged processes, new intellectual property (IP), and novel natural products (microbial collection)

Flexible Scale, Customization and Downstream Capabilities

With over 20 years of experience, Curia excels in manufacturing, isolating and purifying complex biological mixtures. Our infrastructure includes reactors ranging from 2L to 7,000L with advanced monitoring tools and broad DSP capabilities.

Key Capabilities Include:

Image shows the different DSP capabilities Curia has to perform purification, including centrifugation, filtration, chromatography, distillation and other analytical tools

Industrial Fermentation and Biotransformation

Curia excels in:

  • Seamlessly integrating biocatalysis with advanced chemical synthesis
  • Creating innovative and efficient processes that optimize both safety and scalability
  • Multidisciplinary approaches to unlock new intellectual property opportunities
  • Downstream process excellence, including scale-up capabilities for large volumes with solvent-optimized processes

Your Product, Our Expertise

Image shows the areas where Curia fermentation team has experience, including Pharmaceutical APIs. consumer goods and specialized products

Curia Network

Curia’s Spanish biotechnology sites contribute fermentation from 5 to 15,000 L, from cell banks and strain improvement through scale-up, plus full downstream processing: aqueous and ATEX-certified organic solvent separation, tangential flow filtration, liquid-liquid extraction and industrial chromatography.

Rozzano Quinto adds GMP fermentation and industrial chromatography to Curia’s Italian footprint, with a multipurpose pilot plant for scale-up from 1 to 60 kg.

Fermentation Frequently Asked Questions