Rozzano, Italy

Curia – Rozzano Quinto, Italy

API development and manufacturing through chemical synthesis and GMP fermentation.

Curia’s Rozzano Quinto facility develops and manufactures APIs and intermediates through both chemical synthesis and fermentation. The site combines 770 cubic meters of synthesis volume and 180 cubic meters of fermentation volume with industrial chromatography and a multipurpose GMP pilot plant, under FDA, AIFA, PMDA and ANVISA inspection.

Facility at a glance

Expertise

180+ experts

An experienced team spanning chemical synthesis, fermentation and purification operations.

Synthesis volume

770 m³

770 m³ of chemical synthesis volume across the site.

Fermentation volume

180 m³

180 m³ of fermentation volume in a GMP-compliant facility.

Reactor range

15 L to 6,200 L

Reactor capacity from 15 to 6,200 L spans development through commercial batches.

Compliance

FDA, AIFA, PMDA and ANVISA inspected

Inspection history across four agencies supports worldwide commercial supply.

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Rozzano Quinto site capabilities overview

What this site does

Purification columns from 500 to 9,700 L

Flash, reverse phase, affinity, size exclusion, adsorption and ion exchange chromatographic processes run on industrial equipment with columns from 500 to 9,700 L.

GMP fermentation across microbial platforms

A GMP-compliant facility specialized in fermentation-based APIs and intermediates produces by bacteria, streptomycetes, yeasts and fungi, with fermenters from 20 to 40 m³.

Pilot plant from 1 to 60 kg

A multipurpose pilot plant with GMP production from 1 to 60 kg, OEB1-OEB3 handling and broad chemistry scope, including alkylation, carries processes from development to commercial manufacture.

Why clients love this site

Synthesis and fermentation on one site

770 m³ of chemical synthesis alongside 180 m³ of GMP fermentation, with industrial-scale purification to match.

Industrial purification depth

Six chromatographic modes on columns up to 9,700 L purify demanding molecules at production scale.

Inspected by four agencies

FDA, AIFA, PMDA and ANVISA inspection history supports global supply.

A defined route to commercial scale

GMP pilot production from 1 to 60 kg with OEB1-3 handling bridges development chemistry into the site’s commercial assets.

How this site fits into Curia’s network

Rozzano Valleambrosia, Italy – Dedicated monobactam manufacture

Curia’s second Rozzano site operates a dedicated monobactam facility with decades of aztreonam manufacturing experience.

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Origgio, Italy – Complex chemical synthesis

Origgio adds hydrogenation to 14 m³, boronic acid chemistry and 549 m³ of synthesis capacity within Curia’s Italian network.

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León & San Cristóbal, Spain – Fermentation and downstream processing

Curia’s Spanish biotechnology sites contribute fermentation from 5 to 15,000 L, from cell banks and strain improvement through scale-up, plus complete downstream processing: aqueous and ATEX-certified organic solvent separation, tangential flow filtration, liquid-liquid extraction and industrial chromatography.