Structural Biology
At Curia, our team of expert protein chemists and structural biologists brings the advanced experience and technology needed to support all your structural biology needs. Partnering with Curia means you’re not just getting a deliverable—you’re accessing a wealth of knowledge that can make a real difference in your protein expression, structural biology, or Structure-Based Drug Development (SBDD) programs.
We collaborate with you to design a pathway to success, whether you need support with a single step or a complete, end-to-end solution.
Our expertise includes:
- Multi-subunit protein complexes
- Protein nucleic acid complexes
- Protein-ligand complexes
- Membrane proteins
- Structure-Based Drug Development
Unlock the potential of your projects with Curia’s comprehensive solutions in protein chemistry and structural biology.
Publications
With 100+ publications in peer reviewed journals including Science, Nature Structural and Molecular Biology and The Journal of Medicinal Chemistry. Examples of the range and quality of our protein scientists contributions to research can be found in our list of publications here.
Structural Biology Publications
Protein Chemistry Publications
Structural Biology Specialties
- Integrated with Curia’s antibody/antibody-conjugate discovery, medicinal chemistry, computer-aided drug design (CADD), in vitro pharmacology and DMPK teams to provide complete Structure-Based Drug Development (SBDD) and Curia’s unique Structure-Driven Drug Development (SD3) solutions for both large (biologic) and small (synthetic) therapeutic molecule development.
- Hit compound qualification for SBDD or SD3 by high-throughput protein crystallography.
- High resolution structures of proteins or protein-ligand complexes by protein crystallography or cryo-EM.
- Binding model development, testing and refinement by iterative cycles of ML/AI-mediated prediction, ligand synthesis and hypothesis test by high resolution protein-ligand structure determination.
- A la carte option to combine the respective strengths of your own and Curia’s capabilities and experience.
- Simple fee-for-service business models with no trailing obligations.
- Absolute transparency, your scientists are able to talk directly to all members of the Curia team assigned to your program.
- Experienced Project Management solutions are available up to and including management of multi-site, multi-disciplinary, international programs.