Subcutaneous injection presents many advantages over IV administration. Yet, attaining the required concentrations for such injections proves daunting, particularly for protein and antibody-based therapeutics. Concentrated protein and antibody solutions can become highly viscous, form undesirable high molecular weight aggregates, or precipitate. In this webinar, we critically review the molecular intricacies behind these challenges and propose a systematic exploration of the formulation space to identify excipients conducive to high concentration formulations.
Key Learning Objectives:
- Delve into the molecular underpinnings of challenges in high concentration formulation development
- Examine the advantages of systematic, data-driven approaches compared to platform approaches
- Assess strategies for achieving high concentration protein formulation
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