Customized mRNA Processing for Improved Therapy Development and Manufacturing

icons/content-types/video webinar

In vitro-transcribed mRNAs have been proven efficient in various therapeutic applications. However, manufacturing them poses challenges due in part to complexity of the molecules as well as the intricate balancing of reagents in the reaction to balance out potency and integrity. In vitro transcription (IVT) and capping reactions are not one-size-fits all, rather they must be tuned to individual molecules based on their composition, structure, and size to truly optimize mRNA development. Optimizing the process is essential for producing high-quality mRNAs needed for vaccines and other therapeutic applications.

In this GEN webinar, Scott Alderucci will discuss ways of leveraging new technologies and experimental design for an optimized, tailored approach to mRNA therapy development. During the webinar, he’ll cover topics such as subject examination, vital methodologies, refining target components, and proper in-process analytics crucial for developing effective mRNA therapies. Key learning objectives for the webinar include:

  • Identify variable/critical components in mRNA production processes.
  • Understand the rationale behind revisiting procedures for mRNA development.
  • Learn the analytics crucial for navigating the mRNA process development for a more potent and comprehensive product.

Ready to move from idea to impact?

Whether you have a question for our team or an opportunity you’re eager to pursue, one of our experts can help you get started.

Contact Us