Parenteral formulations are broadly characterized as sterile solutions, suspensions, emulsions, and powders for reconstitution for injection or infusion; they are administered directly to subjects, entering the systemic circulation and typically providing rapid onset of action in comparison to orally administered products. Small-volume parenteral products are generally presented in vials or ready-to-use pre-filled syringes, providing ease-of-use in the clinical setting or for patient self-administration. The path to delivering these stable, apparently simple solution, suspension, or emulsion formulations is multi-faceted and requires a constant focus on key control measures through pre-formulation development to commercialization.View article
More from Curia
In the fall of 2021, the Delta variant of SARS-CoV-2 was the dominant strain in the US, being both more contagious than previous variants and more likely to lead to “long COVID” than subsequent Omicron variants. Here we describe the discovery and...