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Synthetic Chemistry Publications

Select publications highlighting Curia Synthetic skills:

  • Allard, M.; Barnes, K.; Chen, X.; Cheung, Y.Y.; Duffy, B.; Heap, C.; Inthavongsay, J.; Johnson, M.; Krishnamoorthy, R.; Manley, C.; Steffke, S.; Varughese, D.; Wang, R.; Wang, Y.; Schwartz, C.E.; “Total synthesis of Resolvin E1” Tetrahedron Letters, 2011, 52, 2623.
  • Amin, R.; Chen, J-X.; Cotterill, I.C.; Emrich, D.; Ganley, D.; Khmelnitsky, Y.L.; McLaws, M.D.; Michels, P.C.; Schwartz, E.; Thomas, D.; Yan, J.; Yang, Q. “Improved Synthesis of the C16-C20 Segment of Resolvin E1 Using Enantioselective Ketone Reduction and Lipase-Catalyzed Resolution” Org. Process Res. Dev. 2013, 17¸915.
  • Krasutsky, S.G.; Jacobo, S.H.; Tweedie, S.R.; Krishnamoorthy, R.; Filatov, A.S. “Route Optimization and Synthesis of Taxadienone” Org. Process Res. Dev. 2015, 19, 284.
  • Huang, Z.; Williams, R. B.; O’Neil-Johnson, M.; Eldridge, G. R.; Mangette, J. E.; Starks, C. M. “A Total Synthesis of Bifidenone, ” J. Org. Chem. 2017, 82, 4235.
  • Wang, H.-J.; Camara, F.; Haber, J. C.; Mangette, J. E. “Synthesis of benzo[6,7][1,4]diazepino[1,2-b]indazol-7(6H)-ones and benzo[f]pyrazolo[1,5-a][1,4]diazepin-4-ones via CuI/L-proline catalyzed intramolecular N2-arylation,” Tetrahedron Lett. 2015, 56, 1030.
  • Wang, H.-J.; Wang, Y.; Camara, F.; Paquette, W. D.; Csakai, A. J.; Mangette, J. E. “Facile synthesis of 6,12b-diaza-dibenzo[a,h]azulen-7-ones and benzo[f]pyrrolo[1,2-a][1,4]diazepin-4-ones via CuI/L-proline catalyzed intramolecular N-arylation,” Tetrahedron Lett. 2011, 52, 541.
  • Mangette, J. E.; Chen, X.; Krishnamoorthy, R.; Vellekoop, A. S.; Csakai, A. J.; Camara, F.; Paquette, W. D.; Wang, H.-J.; Takahashi, H.; Fleck, R.; Roth, G. P.; “2-Trifluoroacetyl aminoindoles as useful intermediates for the preparation of 2-acylamino indoles,” Tetrahedron Lett. 2011, 52, 1292.
  • Johnson, M. R.; Gauuan, J. F.; Guo, C.; Guzzo, P. R.; Le, V.-D.; Shenoy, R. A.; Hamby, J.; Roark, H.; Stier, M.; Mangette, J. E. “Synthesis and characterization of novel bi- and tricyclic α-amino acids,” Synth. Commun. 2011, 41, 2769.
  • Mangette , J. E.; Johnson, M. R.; Le, V.-D.; Shenoy, R. A.; Roark, H.; Stier, M.; Belliotti, T.; Capiris, T.; Guzzo, P, R. “The preparation of optically active α-amino 4H-[1,2,4]oxadiazol-5-ones from optically active α-amino acids,” Tetrahedron 2009, 65, 9536.