Cell Line Development
Curia offers advanced cell line development methods to rapidly move programs from DNA to RCB in weeks utilizing methods to ensure clonality and efficient titer across multiple platforms.
Mammalian cell line development needs innovative technologies to ensure the cell line offers ensured clonality to maximize yields while delivering the necessary clonality to ensure reproducibility from culture to culture to developing a Master Cell Bank
Our Technological Approach
- Electroporation to ensure efficient delivery of desired genes of interest to the cellular fabric
- Single cell plating to isolate multiple expressors for evaluation by our accurate analytics
- Cellular imaging to monitor proliferation of a consistent monoclonal cell line
Features
- Stable transfections to CHO-GSN℠ and CHOZN® cell lines
- Single cell cloning and monitoring for production of stable research cell lines
- Proven stability >60 generations
- Documented progression of research to master cell bank implementation
