Downstream Process Development
Curia provides downstream process development (DSP) services which maximize purity and recovery across an array of molecules.
Our technical team has developed purification schemes for hundreds of unique proteins for pre-clinical material. Our platform processes are designed to maximize purity and yield, while minimizing the time between development and toxicology studies. The developed processes are tailored to meet your program’s specifications.
Curia Offers Two Standard DSP Platforms
- Fc fusion proteins and antibodies (bi- and tri-specifics)
- Proteins (cytokines, growth factors, anticoagulants, vaccines, enzymes)
Services Include
- Services can be performed in parallel with upstream and analytical development services to reduce the time between development and toxicology studies:
- Chromatography capabilities include all modalities (affinity, IEX, HIC, RP, MMC)
- Virus inactivation (pH and detergent)
- Ultrafiltration and Diafiltration
- Viral removal
We also support clients with:
- Direct communication with our technical team
- Weekly updates and reports detailing your program’s advancement