Drug Metabolism and Pharmacokinetics (DMPK)

Curia’s DMPK scientists deliver expert solutions for your drug discovery programs. Providing bioanalytical methods development, in vitro ADMET testing and in vivo PK and PD services that span all stages of drug discovery up to candidate selection.

In vitro ADMET and PK/PD Services by Program Phase

In vitro ADMET Services by Type of Analysis Desired (Part 1)

In vitro ADMET Services by Type of Analysis Desired (Part 2)

Your compounds will be in the safe hands of an experienced team with strong problem-solving skills and expertise in a large variety of the assays and techniques used to assess drug liability, bioavailability, distribution, metabolism and excretion.

Our complete suite of services includes:

• Comprehensive set of DMPK assays, weekly sample submission & test an option
• Drug metabolite identification, synthesis & bioanalysis
• Expert pre-clinical IND-enabling program support
• Seamless integration & coordination with chemistry and biology teams (Curia’s or yours)
• Bioanalytical methods development & PK/PD study sample analysis for both synthetics and biologics (mAbs)
• Modeling by WinNonlin
• Sciex™ LC-MS Triple TOF and QQQ (MS/MS) systems
• Agilent™ RapidFire SPE-MS/MS & LC-MS/MS systems

Partner with Curia for a best-in-class experience.