Insights
fact sheet
Amorphous Solids: Implications for Solubility and Stability
It is important to have both a clear, science-based understanding of how the amorphous active drug is formed and also a comprehensive characterization of its fundamental properties, such as Tg, water vapor sorption, and relaxation time as a function...
article
Mogroside Via1, New Isomer of Mogroside VI Isolated From Luo Han Guo
Two isomers of Mogroside VI, Mogroside VIa1 (1) and Mogroside VIa (2), were isolated from the extracts of Luo Han Guo. Compound 1 is a newly isolated isomer of Mogroside VI. We report here detailed structural confirmation of the structures of 1 and 2...
infographic
Container Closure Integrity USP <1207>
Curia has remained on the cutting-edge of package testing technology with state-of-the-art programs for assessing package system integrity. Within the pharmaceutical industry Container Closure Integrity Testing (CCIT) is crucial in ensuring safety an...
webinar
Time for a Change?
Demands to rapidly advance drugs while minimizing cost as well as maintaining sterility assurance and high safety standards are accelerating the pace of change across the fill/finish industry. As medicines shift from one-size-fits-all treatments to...
fact sheet
Alcohol Induced Dose Dumping Fact Sheet
Curia provides cGMP dissolution support for APIs and a wide variety of dosage forms in various buffered, biorelevant, and mixed organic-phase media. We have capability with various USP dissolution apparatus, including multi scale and automated rota...
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Creating Compound Screening Libraries that Address the Challenges of Drug Discovery
From target discovery through launching a finished product to market, developing a new drug is a complex process which takes on average 10-15 years and costs around 2.6 billion dollars. Early on, this process often involves a high-throughput screenin...
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Comparison of Neisseria gonorrhoeae minimum inhibitory concentrations obtained using agar dilution versus microbroth dilution methods
With increasing antibiotic resistance observed amongst clinical isolates of Neisseria gonorrhoeae, the second most prevalent sexually transmitted bacterial disease in the United States, there is still a need for antimicrobial susceptibility testing...
publications patents
Selected AMRI Publications and Patents from 2005–2019
Between 2005 and 2019, there have been over 350 published pieces and nearly 300 patents that AMRI has released.
publications patents
2019: A Year in Review — AMRI's Contributions to Science
The following research articles appeared in peer-reviewed scientific journals that described innovations conceived by AMRI scientists. In most of these cases, these manuscripts were written by AMRI lead authors to communicate independent research, or...
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Active Pharmaceutical Ingredients (APIs)
A panel of experts share their views on some of the critical issues facing the pharmaceutical industry in regards to API sourcing, new API technical services or manufacturing technologies, guidance on choosing a supplier for API research/development...
webinar
Choosing the Right CDMO for HPAPI Development & Manufacturing
Are you looking for the right contract development and manufacturing organization (CDMO) to develop and manufacture your high potency active pharmaceutical ingredients (HPAPIs)? Or have you been unsure about the CDMO you’re currently working with...
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The PO13 crystal structure of ROY
A novel polymorph of ROY was found by thermal methods. The crystal structure was solved by matching calculated powder X-ray diffraction patterns from a previously published crystal structure prediction to the experimental data. The structure was furt...