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The term amorphous is used loosely in the pharmaceutical industry. A strict definition would limit amorphous to those materials which truly have no long range order, only the short range order characteristic of liquids. However, the term is popular...

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It is important to have both a clear, science-based understanding of how the amorphous active drug is formed and also a comprehensive characterization of its fundamental properties, such as Tg, water vapor sorption, and relaxation time as a function...

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Two isomers of Mogroside VI, Mogroside VIa1 (1) and Mogroside VIa (2), were isolated from the extracts of Luo Han Guo. Compound 1 is a newly isolated isomer of Mogroside VI. We report here detailed structural confirmation of the structures of 1 and 2...

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AMRI has remained on the cutting-edge of package testing technology with state-of-the-art programs for assessing package system integrity. Within the pharmaceutical industry Container Closure Integrity Testing (CCIT) is crucial in ensuring safety and...

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Demands to rapidly advance drugs while minimizing cost as well as maintaining sterility assurance and high safety standards are accelerating the pace of change across the fill/finish industry.  As medicines shift from one-size-fits-all treatments to...

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AMRI provides cGMP dissolution support for APIs and a wide variety of dosage forms in various buffered, biorelevant, and mixed organic-phase media.  We have capability with various USP dissolution apparatus, including multi scale and automated rotat...

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From target discovery through launching a finished product to market, developing a new drug is a complex process which takes on average 10-15 years and costs around 2.6 billion dollars. Early on, this process often involves a high-throughput screenin...

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With increasing antibiotic resistance observed amongst clinical isolates of Neisseria gonorrhoeae, the second most prevalent sexually transmitted bacterial disease in the United States, there is still a need for antimicrobial susceptibility testing...

040E93C7-D189-4233-A102-58C0580BE529 publications patents

Between 2005 and 2019, there have been over 350 published pieces and nearly 300 patents that AMRI has released.

040E93C7-D189-4233-A102-58C0580BE529 publications patents

The following research articles appeared in peer-reviewed scientific journals that described innovations conceived by AMRI scientists. In most of these cases, these manuscripts were written by AMRI lead authors to communicate independent research, or...