Title:
Thermostability Analysis by DSF

Description:
Thermostability Analysis by DSF

Scope:
1. The antibody/protein sample is injected into either the Nano DSC instrument (TA instrument) or UNcle (Unchained Labs).

2. The Tm (melting temperature where 50% protein is denatured) is calculated after deconvolution using the analytical software

Note: the above quoted prices are based on analysis using Curia’s standardized methods, proven to work for a majority of antibodies and proteins. Method development may be necessary for atypical proteins with unique properties for an additional fee

Deliverable:
Report containing heat stability data for test articles as measured by Tm (thermal transition mid-point).

Material Required:
100µL of purified protein at ≥ 1mg/mL
(Optional) 10mL blank buffer formulation
Please complete and include a Bioanalytical Sample Submission Form with any proteins or antibodies you send to Curia for analysis

Timeline:
1 week

Price:
$440