Aqueous Solubility, Shake Flask

Assay System:

  • Phosphate Buffer Saline pH 7.4 (PBS); other aqueous systems available upon request.
  • Solubility measured by incubating test compound in PBS for 24 h, followed by determination of dissolved concentration against a calibration curve.

Assay Conditions:

Test Compound Concentration 100 µM
Percent Organic Solvent in Incubation No organic solvent added
Incubation Time 24 hours
pH 7.4 or as requested
Temperature Ambient
Positive Control Verapamil and Tamoxifen
Analysis UV/VIS Absorbance or LC-MS (LC-MS/MS if necessary)
Number of Repeats 2

Deliverable: Solubility of test compound (µM).

Test Compound Requirement: 1-2 mg dry powder.

*If you choose "Other", please use the comments section below to request your desired system.
You must select at least one detection method.