CHO Stable Cell Line Development
Curia provides stable CHO cell line development services for diagnostic or therapeutic products.
Developed from the CHO-K1 parental cell line, Curia offers the CHO-GSN℠ stable cell line expression platform for the production of proteins and antibodies. CHO-GSN℠ is a glutamine synthetase (GS) knockout cell line for the generation of a research cell bank (RCB) and future use as a manufacturing cell line for commercial products.
- Royalty-free, no commercial milestone payments
- CHO-K1 GS knockout with stronger GS selection, high titers
- Generational stability >80 generations demonstrated
- Established track record; multi-programs in clinical stages
As a service, RCBs are generated under the following workflow
After the RCB is developed, Curia offers characterization services, MCB generation, and process development service
To learn about Curia GMP manufacturing for antibodies/proteins and mRNA, please click here.
Are you looking to accelerate your drug development program? If you would like to speak to a member of our expert team, please contact Curia here.