Synthetic and Medicinal Chemistry
For 30 years, Curia has provided expertise in synthetic and medicinal chemistry, driven by the goal of accelerating your program on the road to the clinic and commercialization. Providing chemistry support that span all stages of drug discovery, from exploratory, hit-to-lead, lead optimization, to candidate selection. We deliver expert solutions to your complex discovery challenges with a proven track record for success, including the development of more than 95 preclinical and clinical candidates. To accelerate your innovation, we combine scientific expertise and leading-edge technology at our integrated drug discovery centers.
Our complete suite of synthetic and medicinal chemistry capabilities includes:
- Integration with discovery, biology and pharmacology to support hit-to-lead identification through candidate selection
- Structure-activity relationships (SARs)/structure-property relationships (SPRs) and novel target development guided by computer-aided drug design (CADD)
- Route design
- Custom synthesis
- Parallel synthesis
- Library design and synthesis, including Curia’s Compound Library Consortium Asymmetric synthesis
- Complex chemistries including eicosanoids, polysaccharides and challenging reactions